by Dr Simona Pop
As we age, the stem cells in our body become less and less efficient. At the age of 60, stem cells show very little activity, becoming slower and releasing less growth factors that are needed to repair our body.
By our mid-70s, we have almost no stem cell activity. This is why it is so difficult for older people to heal from injuries.
Most stem cell drug companies work on injecting stem cells from a younger donor into an older recipient. But there is a way to ‘reset’ our own stem cells and make them start behaving like younger, healthier cells.
This would be incredibly safe, highly effective, and extremely cheap. Imagine a product that can activate your stem cells, returning those cells to a healthier, younger state. This would represent a whole new level of vitality, with improvements in energy, sleep, reduced pain, reduced appearance of lines and wrinkles, and supporting faster wound healing, just to name a few of the benefits.
A successful anti-aging program is specific to the needs and adapted to the body. Doctors can help patients create an individualized anti-aging course that will keep them healthy for years.
What are the similarities and differences between embryonic and adult stem cells?
- Human embryonic and adult stem cells have advantages and disadvantages regarding potential use for cell-based regenerative therapies. Of course, adult and embryonic stem cells differ in the number and type of differentiated cell types they can become.
- Embryonic stem cells can become all cell types of the body because they are pluripotent.
- Adult stem cells are generally limited to differentiating into different cell types of their tissue of origin. However, some evidence suggests that adult stem cell plasticity may exist, increasing the number of cell types a given adult stem cell can become.
Large numbers of embryonic stem cells can be grown relatively easily in culture, while adult stem cells are rare in mature tissues and methods for expanding their numbers in cell culture have not yet been worked out. This is an important distinction, as large numbers of cells are needed for stem cell replacement therapies.
Stem cells are thought to mediate repair via five primary mechanisms:
1) providing an anti-inflammatory effect
2) homing to damaged tissues and recruiting other cells, such as endothelial progenitor cells, that are necessary for tissue growth
3) supporting tissue remodeling over scar formation
4) inhibiting apoptosis, and
5) differentiating into bone, cartilage, tendon, and ligament tissue.
In conclusion
To further enrich blood supply to the damaged areas, and consequently promote tissue regeneration, platelet-rich plasma could be used in conjunction with stem cell transplantation.
The efficacy of some stem cell populations may also be affected by the method of delivery; for instance, to regenerate bone, stem cells are often introduced in a scaffold where they produce the minerals necessary for generation of functional bone.
Stem cells have been shown to have low immunogenicity due to the relatively low number of MHC molecules found on their surface. In addition, they have been found to secrete chemokines that alter the immune response and promote tolerance of the new tissue. This allows for allogeneic treatments to be performed without a high rejection risk.
